有研究发现b-CD能够识别手性伯胺,并对其催化作用有促进作用。超分子与手性伯胺的相互作用与立体构象能够用ROESY进行表征。在2到20mM浓度范围内,手性二胺以单体形式存在,这为DOSY结果所证实。这说明b-CD与手性伯胺的相互作用主要与手性二胺的单体形式有关。相关结果见JACS 2010, 132, 7216–7228。
Figure 8. ROESY spectrum and conformation of (a) CD-1 (0.02 M) in D2O; (b) CD-1 (0.02 M) in acetate buffer (pH ) 4.80); (c) CD-2 (0.02 M) in D2O; and (d) CD-2 (0.02 M) in acetate buffer (pH ) 4.80). (600 M)
Figure S10 The DOSY spectrum of CD-1 (D2O, T = 298 K, 600 M) under 2 mM (a) and 20 mM (b), showing the same diffusion coefficient.
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